While everyone is unique, many people have lost 15% or more of their starting body weight with tirzepatide.

A clinical trial of over 2,500 people who are considered obese or overweight experienced significant weight loss in the first of tirzepatide’s weight loss studies. Those treated with tirzepatide had an average weight loss of 15% to 20% of their starting body weight over 72 weeks (about 16.5 months). This worked out to an average weight loss of 34 lbs to 48 lbs. Those taking the placebo (an injection with no medication in it) only had an average of 3% weight loss.

What’s more, over a third of those taking the highest tirzepatide (15 mg per week) lost at least 25% of their starting body weight (over 58 lbs).