Low-Dose Naltrexone (LDN)
Starting at $26.50/mo 0% APR with Affirm®
Low-Dose Naltrexone (LDN) is an innovative therapy that uses a much smaller dose of the medication naltrexone — originally developed for addiction treatment — to help regulate the immune system, balance inflammation, and improve overall hormonal and metabolic health.
Emerging research and clinical experience suggest LDN may support women with PCOS, autoimmune conditions, and chronic inflammation by helping the body reset its natural endorphin response. This makes it a promising option for symptom relief, improved mood, and better energy regulation.
At low doses, naltrexone briefly blocks opioid receptors, prompting the body to increase production of endorphins and upregulate immune balance once the block wears off. These endorphins don’t just influence mood — they also play a role in regulating the immune system, inflammation, and even reproductive hormone pathways.
For women with PCOS or hormonal imbalances, LDN’s effects may help reduce systemic inflammation, improve insulin sensitivity, and support a healthier hormonal environment. Patients also report better energy, mood stability, and improved resilience to stress.
- Improved hormone balance and potential support for menstrual regularity
- Reduction in inflammation and immune system overactivity
- Enhanced mood stability and energy through increased endorphin levels
- Support for insulin sensitivity and metabolic balance (adjunct in PCOS management)
- Well tolerated, with minimal side effects compared to higher-dose medications
- Non-addictive and affordable long-term option
Dosing Options:
Low-Dose Naltrexone (LDN)
Starting at $26.50/mo 0% APR with Affirm®
Low-Dose Naltrexone (LDN) is an innovative therapy that uses a much smaller dose of the medication naltrexone — originally developed for addiction treatment — to help regulate the immune system, balance inflammation, and improve overall hormonal and metabolic health.
Emerging research and clinical experience suggest LDN may support women with PCOS, autoimmune conditions, and chronic inflammation by helping the body reset its natural endorphin response. This makes it a promising option for symptom relief, improved mood, and better energy regulation.
At low doses, naltrexone briefly blocks opioid receptors, prompting the body to increase production of endorphins and upregulate immune balance once the block wears off. These endorphins don’t just influence mood — they also play a role in regulating the immune system, inflammation, and even reproductive hormone pathways.
For women with PCOS or hormonal imbalances, LDN’s effects may help reduce systemic inflammation, improve insulin sensitivity, and support a healthier hormonal environment. Patients also report better energy, mood stability, and improved resilience to stress.
- Improved hormone balance and potential support for menstrual regularity
- Reduction in inflammation and immune system overactivity
- Enhanced mood stability and energy through increased endorphin levels
- Support for insulin sensitivity and metabolic balance (adjunct in PCOS management)
- Well tolerated, with minimal side effects compared to higher-dose medications
- Non-addictive and affordable long-term option
Dosing Options:
Lose up to 22% of your body weight using our evidence-based medications and programs backed by science
Clinically proven for weight loss and glycemic control
Curbs appetite and keeps you feeling fuller, longer
Optimize with metabolic testing and support
Available Plans
All of Momentum Health’s programs use the most up-to-date medical knowledge to give you the best results possible. Meet our care team of board certified physicians licensed in your state!
4 Weeks Starter
$129
Billed for 4 Weeks
FEATURES
8 Weeks Starter
$239
Billed for 8 Weeks
FEATURES
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
12 Weeks Starter
$329
Billed for 12 Weeks
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
- Receive a monthly delivery of compounded Semaglutide GLP-1 prescription medication and supplies right to your door, with easy refills. (Note: The first month includes the 0.25 mg starter dose.)
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
- Receive a monthly delivery of compounded Semaglutide GLP-1 prescription medication and supplies right to your door, with easy refills. (Note: The first month includes the 0.25 mg starter dose.)
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
Available Plans
All of Momentum Health’s programs use the most up-to-date medical knowledge to give you the best results possible. Meet our care team of board certified physicians licensed in your state!
Month to Month Starter
$275 /mo
Monthly Subscription
FEATURES
Month to Month Subscription
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
2 Month Starter
$250 /mo
Billed for 2 Months
FEATURES
Save By Bundling 2 Months
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
3 Month Starter
$225 /mo
Billed for 3 Months
FEATURES
Save By Bundling 3 Months
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
- Receive a monthly delivery of compounded Semaglutide GLP-1 prescription medication and supplies right to your door, with easy refills. (Note: The first month includes the 0.25 mg starter dose.)
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
Maintenance MTM Plan
$325 /mo
$233 /mo billed monthly
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
Maintenance 2 Month Plan
$301 /mo bimonthly
$266/mo billed quarterly
Bundle and save with our 2 month maintenance plan! (save $30 on shipping + $50 on medication ☺️)
Receive an initial two-month supply of compounded Semaglutide GLP-1 medication, with automatic shipments to ensure no delays—all while saving hundreds of dollars compared to monthly purchases.
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
Maintenance 3 Month Plan
$275 /mo quarterly
$266/mo billed quarterly
Enjoy a hassle-free, 3-month supply program with a simple telehealth visit to get started. Billed at $825 every 3 months.
(savings of $135 😘)
Receive an initial two-month supply of compounded Semaglutide GLP-1 medication, followed by your third vial at the end of month two, with automatic shipments to ensure no delays—all while saving hundreds of dollars compared to monthly purchases.
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
Related Products
Who is NOT Eligible or Allergy:
- Pregnant or breastfeeding women
- Patients with liver or kidney disease
- People with heart conditions
- Under 18 years old
Exclusion States:
- California
- New York
Online Onboarding Questionaire
Step 2
Online Telehealth Review
Finish your medical questionnaire, and a board-certified physician will provide a same-day* consultation to thoroughly evaluate your health and weight-loss goals.
Step 3
Receive Medication
Online Onboarding Questionaire
No more annoying appointments! After placing your order, you will complete a medical questionnaire about your health and weight-loss goals—all from the comfort of your phone.
Online Telehealth Review
Finish your medical questionnaire, and a board-certified physician will provide a same-day* consultation to thoroughly evaluate your health and weight-loss goals.
Receive Medication
Once your prescription is approved, a pharmacist will prepare your medication and ship it to your door in 3-5 business days. Plus, you’ll have 24/7 access to your care team, educational resources, and so much more.
Science Backed.
Medically Approved.
All of Momentum Health’s programs use the most up-to-date medical knowledge to give you the best results possible. Meet our care team of board certified physicians licensed in your state!
Momentum’s Mission
At Momentum Health, we are committed to delivering results in your pursuit of weight loss and metabolic health. Our platform provides seamless access to advanced GLP-1 medications, such as compounded Semaglutide (found in Ozempic® and Wegovy®) and Tirzepatide (found in Mounjaro® and Zepbound™), directly from your mobile device. Beyond medication, we ensure clinical oversight, optional metabolic testing, and continuous support from board-certified physicians. We also offer dietary guidance and, through our health coaches, equip you with all the tools necessary to achieve a healthier, more vibrant, purpose-driven life. Partner with us, and let us drive your success toward a transformed you—Please remember one thing! We Get Results!
Our commitment to compliance
Compounded Semaglutide refers to a medication meticulously formulated FDA-licensed compounding facility, in strict accordance with a prescription issued by a licensed healthcare professional. These compounded pharmaceuticals are required and are subjected to comprehensive testing to verify potency, sterility, and purity.
Momentum Health 360 partners solely with licensed sterile compounding pharmacies throughout the United States, ensuring unwavering adherence to the highest standards.
Still Have Questions?
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FAQ
Have any questions?
Find answers here!
What is Low-Dose Naltrexone (LDN)?
A low-dose version of naltrexone used off-label to help regulate the immune system, reduce inflammation, and improve metabolic and hormonal health.
Is LDN safe for women with PCOS?
Yes — while not FDA-approved specifically for PCOS, early studies and clinical reports suggest LDN may support metabolic balance and inflammation in PCOS patients.
How is LDN taken?
Usually as an oral capsule at bedtime. Your clinician will adjust dosing based on your response.
Will LDN help with weight loss?
It is not a direct weight-loss drug, but by improving inflammation and insulin sensitivity, it may support weight management alongside lifestyle changes or GLP-1 therapy.
What side effects should I expect?
LDN is generally well tolerated. The most common side effects are vivid dreams or mild sleep disturbances, which often improve with dose adjustment.
How soon will I notice results?
Some patients notice improved sleep, energy, and mood within weeks. Hormonal and metabolic improvements may take 2–3 months.
Can I use LDN with other PCOS treatments?
Yes. It may complement GLP-1s, metformin, inositols, and lifestyle changes. Always check with your provider.
Is LDN addictive?
No. At low doses, naltrexone has no addictive properties.
Do I need labs before starting?
Basic labs may be recommended to monitor liver function and overall health, especially if combining with other therapies.
Is LDN FDA-approved for PCOS?
No — LDN is an off-label therapy. That means it’s not officially approved for PCOS but is prescribed based on promising clinical evidence and physician judgment.
