Low-Dose Naltrexone (LDN)
Starting at $16.00/mo 0% APR with Affirm®
Low-Dose Naltrexone (LDN) is an innovative therapy that uses a much smaller dose of the medication naltrexone — originally developed for addiction treatment — to help regulate the immune system, balance inflammation, and improve overall hormonal and metabolic health.
Emerging research and clinical experience suggest LDN may support women with PCOS, autoimmune conditions, and chronic inflammation by helping the body reset its natural endorphin response. This makes it a promising option for symptom relief, improved mood, and better energy regulation.
At low doses, naltrexone briefly blocks opioid receptors, prompting the body to increase production of endorphins and upregulate immune balance once the block wears off. These endorphins don’t just influence mood — they also play a role in regulating the immune system, inflammation, and even reproductive hormone pathways.
For women with PCOS or hormonal imbalances, LDN’s effects may help reduce systemic inflammation, improve insulin sensitivity, and support a healthier hormonal environment. Patients also report better energy, mood stability, and improved resilience to stress.
- Improved hormone balance and potential support for menstrual regularity
- Reduction in inflammation and immune system overactivity
- Enhanced mood stability and energy through increased endorphin levels
- Support for insulin sensitivity and metabolic balance (adjunct in PCOS management)
- Well tolerated, with minimal side effects compared to higher-dose medications
- Non-addictive and affordable long-term option
Dosing Options:
A medically guided GLP-1 program built to help you work toward your weight goals with real clinical support.
Designed to support weight management and healthy blood-sugar balance.
Curbs appetite and keeps you feeling fuller, longer
Optimize with metabolic testing and support
Available Plans
All of Momentum Health’s programs use the most up-to-date medical knowledge to give you the best results possible. Meet our care team of board certified physicians licensed in your state!
1 Month Starter
$129
Billed for 1 Month
FEATURES
2 Months Starter
$239
Billed for 2 Months
FEATURES
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
3 Months Starter
$329
Billed for 3 Months
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
- Receive a monthly delivery of compounded Semaglutide GLP-1 prescription medication and supplies right to your door, with easy refills. (Note: The first month includes the 0.25 mg starter dose.)
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
- Receive a monthly delivery of compounded Semaglutide GLP-1 prescription medication and supplies right to your door, with easy refills. (Note: The first month includes the 0.25 mg starter dose.)
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
FEATURES
Includes:
- Doctor
- Syringes
- Medication
- Alcohol Swabs
Each batch undergoes extensive quality checks by licensed, certified pharmacists to ensure the highest standards.
Enjoy ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, diet tips, and more.
6 Months Maintenance
$66
Billed for 6 Months
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
FEATURES
Hassle-free, month to month maintenance. (For higher doses/ 3 month minimum requirement)
Month to month supply of compounded Semaglutide GLP-1 medication!
Each batch of medication is thoroughly inspected by licensed, certified pharmacists to meet the highest standards.
Benefit from ongoing support, including unlimited messaging with your provider for dosage and side effect discussions, personalized nutrition guidance, and custom exercise videos.
Related Products
If you have any questions. We're here to help!
Low-Dose Naltrexone (LDN)
No more annoying appointments! After placing your order, you will complete a medical questionnaire about your health and weight-loss goals—all from the comfort of your phone.
Online Telehealth Review
Finish your medical questionnaire, and a board-certified physician will provide a same-day* consultation to thoroughly evaluate your health and weight-loss goals.
Receive Medication
Once your prescription is approved, a pharmacist will prepare your medication and ship it to your door in 3-5 business days. Plus, you’ll have 24/7 access to your care team, educational resources, and so much more.
Backed by Science.
Guided by Doctors.
All of Momentum Health’s programs use the most up-to-date medical knowledge to give you the best results possible. Meet our care team of board certified physicians licensed in your state!
Momentum’s Mission
At Momentum Health, we're here to support your weight-loss and metabolic health journey from start to finish. Our platform gives you streamlined telehealth access to GLP-1 medications — including compounded semaglutide, tirzepatide, and liraglutide — prescribed by board-certified physicians licensed in your state. Beyond the medication, you get clinical oversight, optional metabolic testing, ongoing provider support, and personalized guidance from our health coaches on nutrition and lifestyle. Our goal is simple: to give you the tools, care, and consistency you need to feel your best. Let's build momentum together.
Our commitment to compliance
Our compounded Low-Dose Naltrexone (LDN) is prepared only after a licensed healthcare provider issues a valid prescription for you. It's compounded at state-licensed U.S. compounding pharmacies that follow strict sterile-compounding standards, and each batch is tested for potency, sterility, and purity. Compounded medications are not FDA-approved, but Momentum Health 360 partners only with reputable, fully licensed pharmacies so you can feel confident in the quality and care behind every order.
Still Have Questions?
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What our members are saying
FAQ
Have any questions?
Find answers here!
What is Low-Dose Naltrexone (LDN)?
A low-dose version of naltrexone used off-label to help regulate the immune system, reduce inflammation, and improve metabolic and hormonal health.
Is LDN safe for women with PCOS?
Yes — while not FDA-approved specifically for PCOS, early studies and clinical reports suggest LDN may support metabolic balance and inflammation in PCOS patients.
How is LDN taken?
Usually as an oral capsule at bedtime. Your clinician will adjust dosing based on your response.
Will LDN help with weight loss?
It is not a direct weight-loss drug, but by improving inflammation and insulin sensitivity, it may support weight management alongside lifestyle changes or GLP-1 therapy.
What side effects should I expect?
LDN is generally well tolerated. The most common side effects are vivid dreams or mild sleep disturbances, which often improve with dose adjustment.
How soon will I notice results?
Some patients notice improved sleep, energy, and mood within weeks. Hormonal and metabolic improvements may take 2–3 months.
Can I use LDN with other PCOS treatments?
Yes. It may complement GLP-1s, metformin, inositols, and lifestyle changes. Always check with your provider.
Is LDN addictive?
No. At low doses, naltrexone has no addictive properties.
Do I need labs before starting?
Basic labs may be recommended to monitor liver function and overall health, especially if combining with other therapies.
Is LDN FDA-approved for PCOS?
No — LDN is an off-label therapy. That means it’s not officially approved for PCOS but is prescribed based on promising clinical evidence and physician judgment.
